Muscle Relaxants are a very large group of medications but baclofen (Lioresal) is the Medications on the “avoid list” will not necessarily worsen dystonia.
Lower potency neuroleptics have a slightly lower risk of dystonia and include:
Alprazolam (Xanax) Midazolam (Versed).
Neuroleptics are a class of drugs normally used to treat mental illness such as psychosis, bipolar disease and depression. Many people with dystonia have depression and a few may be exposed to these drugs. Neuroleptics work by blocking the transmission of dopamine in the brain. There are several types of neuroleptics. “High potency” neuroleptics are the most likely to cause or worsen dystonia.